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Building on this, Encoded Therapeutics is currently conducting a Phase I/II clinical trial (NCT05419492) to evaluate the safety and efficacy of EXT101 in infants with SCN1A-positive DS

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Although our primary endpoints of SARS-CoV-2 infection rates in Cohort 1 and disease progression in Cohort 2 were unmet, our analysis of the secondary endpoints suggests that LCLT supplementation modulates coagulation via increased platelet count and decreased fibrinogen levels